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 Dr.
Christophe Nguyen
Biographical information
Dr. Nguyen is a new addition to the Spartanburg surgical
community and specializes in general and thoracic surgical
oncology. He developed an interest in surgical oncology during
his general surgical residency at the Medical University of South
Carolina, and spent two additional years conducting cancer
research at the Hollings Cancer Center. He then further pursued
his interest in oncology by completing a two-year Surgical
Oncology Fellowship at Fox Chase Cancer Center.
Dr. Nguyen has published numerous works in both basic science and
clinical peer-review journals. He has also presented such work at
international meetings such as the American College of Surgeons
Clinical Congress, the Society of Surgical Oncology and the
American Association for Cancer Research.
Although his training spans the entire field of surgical oncology
(head and neck, breast, thoracic and GI disease), he has
developed particular interest in the surgical management of
thoracic and gastrointestinal malignancies. Dr. Nguyen has
introduced several new minimally-invasive surgical techniques to
SRMC such as laparoscopic colorectal and liver surgery.
Furthermore, he is one of the only thoracic surgeons in the state
performing video-assisted (VATS) lobectomies.
Dr. Nguyen is credentialed by the MD Anderson Network and is an
active member of the Society of Surgical Oncology. He
participates regularly at the Gibbs Cancer Center tumor
conferences, as well as resident didactic conferences.
Medical School: Baylor College of Medicine, Houston, TX.
General Surgery Residency: Medical University of South Carolina
Research Fellowship: Hollings Cancer Center, Charleston, SC.
Surgical Oncology Fellowship: Fox Chase Cancer Center,
Philadelphia, PA.
Certification: American Board of Surgery
Clinical Interests: General Surgical Oncology; Foregut-
esophagus/stomach cancer; Hepato-biliary and Pancreas; Liver
metastases; RFA, pancreatic cancer; Thoracic Oncology (Lung
cancer, VATS, mediastinoscopy)
On a personal note
Although cancer can develop at many sites throughout the body,
the most common cancers that we face develop in solid organs
(lung, breast, colon, etc.). Often, surgical removal of a cancer
can afford patients a chance of cure or prolonged survival. The
field of surgical oncology is devoted exclusively to the surgical
management of cancer. This subspecialty requires several more
years of training after the completion of a general surgery
residency. Less than 50 surgical oncologists a year complete
their training and enter surgical practice compared to over 1,000
general surgeons a year. This additional training allows surgeons
to tackle difficult cancers (such as esophagus, lung, liver and
pancreas tumors) safely and successfully. Surgical oncologists
approach these cancers not only with the latest surgical
techniques, but with greater understanding of the underlying
tumor biology. We collaborate closely with our medical and
radiation oncology colleagues and stay at the forefront of
emerging and exciting treatment strategies.
I have spent nearly a decade in surgical training so as to offer
my cancer patients the most technically advanced and
sophisticated operations possible. As an advocate of quality of
life after surgery, I routinely incorporate minimally-invasive
(laparoscopy, thoracoscopy) techniques. My patients not only
receive the best cancer operation possible, but often benefit
from less post-operative pain and earlier recovery. Sometimes,
chemotherapy and radiation are needed after surgery, and a quick
recovery allows these patients to receive additional treatment
without delay.
In addition to my surgical skill, I offer my patients and their
families my deepest sympathy and understanding. From the first
office visit through the post-surgery recovery and beyond, my
goal is to ensure that patients and their families completely
understand the surgical process and all available treatment
options. Unlike other disciplines within medicine, the practice
of surgical oncology is unique as it combines advanced surgical
technique with compassion in the pursuit of one relentless goal:
the cure of cancer.
Scientific Publications
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Nguyen CL, Scott WJ and Goldberg M. Radiofrequency ablation of
primary and metastatic lung malignancies. Ann Thorac Surg
82:365-71, 2006
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Nguyen CL, Scott WJ, Young N, Rader T, Giles LR, Goldberg M.
Radiofrequency ablation of primary lung cancer: Results from an
ablate and resect pilot study. Chest 128:3507-11, 2005
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Nguyen CL, Barnett CC. Cancer of unknown primary. In: McIntyre
RC, Stiegmann GV, Eiseman B, eds. Surgical Decision Making.
Philadelphia: W.B. Saunders Company, 256-57, 2004
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Salem ML, Kadima AN, Zhou Y, Rubinstein MP, Nguyen CL,
Demcheva M, Vournakis JN, Cole DJ, Gillanders WE. Paracrine
release of interleukin-12 (IL-12) stimulates interferon-ã
production by antigen presenting cells and dramatically enhances
the antigen-specific T cell response following vaccination with a
novel peptide-based cancer vaccine. Journal of Immunology
172:5159-67, 2004
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Nguyen CL, Salem ML, Bui JT, Rubinstein MP, Demcheva M,
Vournakis JN, Cole DJ, Gillanders WE. Mechanisms of enhanced
antigen-specific T cell response following vaccination with a
novel peptide-based cancer vaccine and systemic interleukin-2
(IL-2). Vaccine 21:2318-28, 2003
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Rubinstein MP, Kadima AN, Salem ML, Nguyen CL, Gillanders WE,
Nishimura MI, Cole DJ. Transfer of TCR genes into mature T cells
is accompanied by the maintenance of parental T cell avidity.
Journal of Immunology 170:1209-17, 2003
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Rubinstein MP, Kadima AN, Salem ML, Nguyen CL, Gillanders WE,
Cole DJ. Systemic administration of IL-15 augments the
antigen-specific primary CD8+ T cell response following
vaccination with peptide-pulsed dendritic cells. Journal of
Immunology 169:4928-35, 2002
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Nguyen CL, Gillanders WE. Biliary drainage update. Current
Surgery 59(5):433-6, 2002
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Nguyen CL, Bui JT, Demcheva M, Vournakis JN, Cole DJ,
Gillanders WE. Sustained release of GM-CSF from a modular
peptide-based cancer vaccine alters vaccine microenvironment and
enhances the antigen-specific T cell response. Journal of
Immunotherapy 24(5):420-9, 2001
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Nguyen CL, Bui JT, Demcheva M, Vournakis JN, Cole DJ,
Gillanders WE. Systemic IL-2 alters trafficking of
antigen-specific T cells and enhances the primary and memory
response to peptide vaccination. Surgical Forum 52:286-88, 2001
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Nguyen CL, McClay EF, Cole DJ, O'Brien PH, Gillanders WE,
Metcalf JS, Maize JC, Baron PL. Melanoma thickness and histology
predict sentinel lymph node status. American Journal of Surgery
181:8-11, 2001
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Baron PL, Nguyen CL. Malignant melanoma. In: Holzheimer RG,
Mannick JA, eds. Surgical Treatment, Evidence-Based and
Problem-Oriented. Munich: W. Zuckschwerdt Verlag, 549-553, 2001
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Nguyen CL, Bui JT, Demcheva M, Vournakis JN, Cole DJ,
Gillanders WE. Paracrine GM-CSF delivery enhances the
antigen-specific T cell response to a novel peptide-based cancer
vaccine. Surgical Forum 51:288-290, 2000
Comments about Dr. Nguyen
"I just wanted to let you know how much your care of me as your
patient was appreciated! I know that my choice of a surgeon was
no accident. The Lord was right there with you, guiding you
through the surgery. You have such a gentle, caring and
compassionate demeanor, all of which, combined with skill makes
for a great doctor! Thanks for being there for myself and my
family"
"Thank you for the care you gave my son. Besides performing the
surgery, I felt that you treated us with respect and compassion.
Your manner put both of us at ease during a stressful and
frightening time, and I thank you"
"This doctor is one of a kind. He explained to me I had a cancer
in my right lung. He is a very caring and compassionate man. With
his expertise and God’s healing hand, they rid me of this cancer.
Dr. Nguyen is a rare man and if you are fortunate to know him,
you know what I mean. He worked on me and still cares for me
after the surgery. He’s a hard working M.D. I would recommend him
to any one I know. I care and love this man for he has changed my
life and my family’s life. Once again, thanks doctor. May God be
with you always"
"Dr. Nguyen is a very caring doctor, the best doctor. He got me
through the hard times. Thanks again Dr. Nguyen. God Bless"
"Your patient and detailed explanations, and your truly caring
and honest demeanor, never once made us feel doubtful or
apprehensive. You treated him as if he was the only patient you
had and never made him feel rushed or hurried. This is rare in
today’s hectic paced society. Under your care, we have come to
fully understand the meaning of a dedicated and caring physician.
The polite, informative and understanding manner in which you
consistently treated us with will never be forgotten"
"Thank you for the tender, loving care you gave Dad…It was a
great comfort to know that he was in your very capable hands. We,
as well as Dad, have nothing but the highest regard for you, not
only in your medical skill and knowledge, but also in the
wonderful way you communicated and cared for all of us. Also,
thank you for your incredible patience with us. You answered so
many questions and helped us in so many ways"
"Words are so inadequate to express our deep appreciation for the
superior medical care, kindness and compassion you showed to my
husband. From our first office visit with you, we knew that God
had sent you to Spartanburg, not only did you provide exceptional
medical care, you also provided the comfort, support and
encouragement all of us needed to see us through"
son Network
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